![]() We will use a predefined layout to add title placeholders and the trendline. Essentially, the line expresses the "trend" of the data, and answers the question, "Is the trend favorable or unfavorable?" The default trendline is linear, and the data points will show an increasing or decreasing line at a steady rate.Įxcel calculates such a line based on the experimental data, and adds it to the chart. A trendline can be added to any data series in an unstacked, 2-D area, bar, column, line, or scatter chart. Trendlines are used to graphically display trends in existing data and to help predict forecasts of future values. This type of chart will not need a legend. This chart needs a descriptive title and axis labels that reflect the purpose of each axis. Press & Drag the chart below the data Adding Titles and a Trendline To select the appropriate chart type, in the Charts group, We will initially create a scatter chart that displays markers. To switch to the INSERT tab, on the Ribbon, So for this Scatter chart, we will omit the column labels from our selected data. ![]() The reason for possibly omitting the column labels is we can assign the labels later, in the chart, and use more appropriate text for this chart than those used as column labels. Here, we may want to select the values from both columns, but not include the column labels in the selection. We are not always restricted to selecting data from the worksheet with its column labels. When charting this data, as with any chart, selecting only the desired data is critical to success. Then we will create a trendline and determine the equation that governs this line. We will create an XY Scatter chart using Excel's charting features. For six months, workshop data was tracked to determine if there might be a correlation between the number of participants who thought the instructor answered questions adequately and the number of participants who thought the workshop was satisfactory. We have data compiled from the University of the Midwest regarding workshop evaluation responses. This type of chart compares at least two sets of values or pairs of data and is used to show a relationship between sets of values. ![]() An XY chart differs from most charts in that it has values along both axes the data points are the intersections between the two data sets. The XY chart, sometimes called a scatter chart, is one of the most commonly used charts for technical data.
0 Comments
See 2023 in music for additional information about bands formed, reformed, disbanded, or on hiatus for deaths of musicians and for links to musical awards. 0:00 / 3:12 Panda Pop Level 3568 Ken Eddy 3.32K subscribers 451 views 2 years ago We reimagined cable. Facebook gives people the power to share and makes the world more open and. Play over 90 levels of bubble action Read More. Use special elemental lantern powers to blow up bubbles. Panda Pop Level 1 Panda Pop Level 2 Panda Pop Level 3 Panda Pop Level 4 Panda Pop Level 5 Panda Pop Level 6 Panda Pop Level 7 Panda Pop Level 8 Panda Pop Level 9. Just Panda Pop to make special striped candy, rainbow and wrapped candy. Shoot 3 or more bubbles to make them pop releasing the Pandas. Everything you want to know about Panda Pop game Panda Pop videos, written guides, plain Panda Pop craziness, Videos and more. 2) In Level 568 beware, hitting a lantern drain will steal all of Mama Panda’s lantern powers Use an anti-lantern to drain to turn all of the drains into. Join Facebook to connect with Panda Pop and others you may know. Panda Pop is a Free Facebook Bubble Shooter game, rescue the panda cubs from the bubbles and make sure they get safely back to mama panda. excluding reissues, remasters, and compilations of previously released recordings, and (2) notable, defined as having received significant coverage from reliable sources independent of the subject. Boosters which help you clear Level 568 of Panda Pop 1) In Panda Pop Level 568 the smoke is an annoying obstacle that covers the screen Use anti-smokes to turn them into glass bubbles. Anonymous stuck on Panda Pop - Bubble Shooter Level 471 tips and strategies. Plan your every pop to rescue cute baby pandas An evil baboon has kidnapped & trapped precious panda pups in the jungle. The following is a list of albums, EPs, and mixtapes released in or scheduled for release in 2023. level 568 level 569 level 570 level 571 level 572 level 573 level 574 level 575 level 576 level 577 level 578 View all levels. You can help by adding missing items with reliable sources. ![]() ![]() Panda: Bubble Shooter is created by LAK Games.This is a dynamic list and may never be able to satisfy particular standards for completeness. excluding reissues, remasters, and compilations of previously released recordings, and (2) notable, defined as having received significant coverage from reliable sources independent of the subject. Use the help of the Long Arrow booster power-up to clear out the most difficult places. The company stated that: Despite Panda Pops having healthier ingredients than many rivals, Panda recognised mums’ concerns and the impact of a fizzy drink in the portfolio on brand perception, said brand manager James Nichols. The following is a list of albums, EPs, and mixtapes released in or scheduled for release in 2023.These albums are (1) original, i.e. Match three or more of the same-colored bubbles to burst them. Hold down the left mouse button or your finger to aim, and release to shoot. The golden rule of parenthood is not letting your kids stay inside of a bubble, so go ahead and burst it! How to play: Destroy 5/10 or 15 balls with one ball and get a points bonus. Help popo the panda use his trusty bambo to shoot the evil balls Match up the same coloured balls to destroy them. ![]() Earn coins, power-ups, treasure chests and daily rewards and even play the Wheel of Fortune mini-game to make your adventure more interesting. How do I turn notifications on/off If you would like to remove or turn on the push notifications, tap the gear button on the upper right corner to reach the Settings. Panda Pop is an online free game on TooGame.Com. Use your aiming skills to burst the matching bubbles and use the various types of power-ups to help you along the way. In this game, you are the father of many little pandas and you must save them by clearing all the levels filled with colorful bubbles. Pandas Pop() method is common in most of the data structures but pop() method is a little bit different from the rest. ![]() Pandas is one of those packages and makes importing and analyzing data much easier. Panda: Bubble Shooter is a bubble shooting puzzle game created by LAK Games. Python is a great language for doing data analysis, primarily because of the fantastic ecosystem of data-centric python packages. ![]() Throughout their time in the 1590s, Kit is mean and denigrating to Diana. He is ecstatic to see his dear friend and the man he loves, Matthew, but when Matthew introduces Diana as his wife, Kit is furious and confused. He was one of Shakespeare's influences and was especially known for his famous work "Doctor Faustus."Ĭhristopher ("Kit") Marlowe is the first person Matthew Clairmont and Diana Bishop meet when they timewalk from their present day to Elizabethan London. ![]() Fernando remarks that Phillipe "hadn't stirred a finger" to avenge her.Kit is a character recognized by historians as having been a real person. Since Louisa's actions in London were not public knowledge outside of the small circle of de Clermonts who already knew of Diana's timewalking abilities, it is only when Diana and Matthew return to Sept Tours that Phillipe's actions in disciplining Louisa and his lack of response to her death make sense to others. After her actions in London, Phillipe sends her to what is later described as "the far reaches of the known world". When Diana asks that the family make sure Louisa is not a danger to anyone before they set her free, Gallowglass de Clermont tells her Phillipe de Clermont will never let her roam again. She is disappointed when Diana will not use magic to erase her memory of the events at Greenwich, and describes blood rage as having "these things crawling in your skull". She has been chained and is being tortured by a stag's head dripping blood just beyond her reach. When Diana arrives with Father Hubbard to intervene, Louisa is not in her right mind. While neither Diana nor her unborn children are seriously injured, Matthew is furious.īoth Louisa and Marlowe are imprisoned in Bedlam by Matthew, who feeds off both of them. When Hancock arrives to help Diana, Louisa reveals to him that she believes Diana to be the witch from the prophecy that Gerbert of Aurillac shared with Ysabeau De Clermont, and will bring down the De Clermonts. After a bit of a struggle Diana is able to (with Corra's help) free herself, telling them exactly how they will die. Louisa states that Diana does not deserve a quick death. Both are under the influence of drugs, and Marlowe begs Louisa to kill Diana quickly to end her control of Matthew immediately, but Louisa loves to torture. Marlowe lures Diana into one of the tilt yards, where he and Louisa use her as a jousting target. Unbeknownst to them, A quite insane & drug using (via blood from intoxicated Marlowe) Louisa has arrived in London, and Christopher Marlowe has been reporting to her his suspicions about the witch who has (in his jealous mind) "bewitched" Matthew. Phillipe de Clermont seems unsure of where Louisa is at the time, "Vienna or Venice" and complains that he cannot keep up with Louisa and her wanderings.Īfter Matthew and Diana return to London from Prague in 1591, they must report on their journey to Queen Elizabeth at the Palace of Greenwich. ![]() When Matthew and Diana visit Sept Tours in 1590, Diana uses Louisa's room until their marriage ceremony. Matthew Clairmont tells her that Louisa went to Barbados intent on making herself "queen of the Indies", despite warnings that her taste for young men would be noticed on a small island. While Louisa herself does not appear in the book, Diana Bishop notices her portrait hanging in the gatehouse of the Old Lodge. ![]() Alternatively, arterial occlusion occurs as a consequence of embolism of blood clots originating from the heart ("cardiogenic" emboli). Arterial embolism occurs when clots then migrate downstream and can affect any organ. In most cases, arterial thrombosis follows rupture of atheroma (a fat-rich deposit in the blood vessel wall), and is therefore referred to as atherothrombosis. Arterial thrombosis Īrterial thrombosis is the formation of a thrombus within an artery. Staphyloccoal or Streptococcal infections of the face, for example nasal or upper lip pustules may thus spread directly into the cavernous sinus, causing stroke-like symptoms of double vision, squint, as well as spread of infection to cause meningitis. The facial veins in this area anastomose with the superior and inferior ophthalmic veins of the orbit, which drain directly posteriorly into the cavernous sinus through the superior orbital fissure. Ĭavernous sinus thrombosis is a specialised form of cerebral venous sinus thrombosis, where there is thrombosis of the cavernous sinus of the basal skull dura, due to the retrograde spread of infection and endothelial damage from the danger triangle of the face. An arterial embolus may travel further down the affected blood vessel, where it can lodge as an embolism. Complications can arise when a venous thromboembolism (commonly called a VTE) lodges in the lung as a pulmonary embolism. This type of embolism is known as a thromboembolism. A piece of either an arterial or a venous thrombus can break off as an embolus, which could then travel through the circulation and lodge somewhere else as an embolism. Venous thrombosis (sometimes called DVT, deep vein thrombosis) leads to a blood clot in the affected part of the body, while arterial thrombosis (and, rarely, severe venous thrombosis) affects the blood supply and leads to damage of the tissue supplied by that artery ( ischemia and necrosis). Thrombosis may occur in veins ( venous thrombosis) or in arteries ( arterial thrombosis). A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting") is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. ![]() ![]() Vascular surgery, internal medicine, pulmonology Wearing compression stockings for two years after the diagnosis of a DVT reduces the chance of developing post thrombotic syndrome (discussed below).Cyanosis of the lower right extremity, resulting from acute arterial thrombosis of the right leg (on the left side of the image) At Palm Clinic in Auckland, NZ we can fit you for the appropriate compression stockings. The better the flow, the less the chance of a blood clot increasing in size and the less retention of fluid in the tissues. Compression stockings: Compression stockings provide external support to the lower leg, which improves flow within the deep veins.These are only given in a hospital setting. These can have serious side effects such as severe bleeding, and so are only ever used when the benefits outweigh the risks. Thrombolytic drugs: Less commonly, thrombolytic drugs are used to help dissolve the DVT.They can stop an existing clot from getting bigger and thereby reduce the risk of it breaking off and travelling to other parts of the body. Anticoagulants: These are blood thinners which affect the blood’s natural ability to clot.Treatment can vary depending on the size and position of the clot. Treatment at Palm Clinic in Auckland, NZ is aimed at minimising the chance of the clot growing and/or moving to other parts of the body. ![]() Context: I purchased an easy harness and 8ft leash set in 1" width, which was the wrong size for my dog. In this case, the cost of returning the products was omitted until I pressed further into why paying $10 for a warranty for a product that is not equal value made sense. Everything should be presented upfront for the customer to process what they would like to do. I am not happy with the explanations that were given in to me in pieces from this company. You can call your bank and sort this out, but in the meantime, I went ahead and issued you an additional refund in the amount of $1 to make up for the fee! I hope this helps, Anna! But in the meantime, if you have any other questions or concerns, please don't hesitate to reach out to us by email! We are always here to help! Sophie TagsforHope "Woof" Team Įdit: A different customer care manager was able to assist me exchange my items. Unfortunately it sometimes happens, as we are located in Canada and some US banks see us an "international" and charge this fee to their customers. Please know that this is not our charge, but an "international fee" imposed by your bank. As for the 99 cent charge, I am sorry that happened. So please allow a few more days for the funds to go back to your account. Credit card companies typically need 3-5 business days to process a refund - it doesn't happen instantly. I am sorry it affected the production of your order, but I see that it is shipped and on it's way to you! According to tracking, it should arrive on April 29 so please be on the lookout for it! I also see that the 15% refund was only issued to you about 3 days ago. We are unfortunately delayed in manufacturing due to a large volume of orders following our harnesses launch. ![]() Hi Anna, Thank you so much for your feedback and I am truly sorry for any trouble! Firstly, I apologize that your order took slightly longer to manufacture than it normally would. ![]() After rebranding from Tencent Gaming Buddy to GameLoop in 2019, we hope to support not only mobile games, but also PC games and web games. With GameLoop, users can download and use hundreds of mobile games and applications on PC for free. GameLoop PCĪs a brand-new game emulator launched in 2018, GameLoop entered the global market and became the best android emulator for brand recognition. Specifically, with a self-innovated AOW engine, exclusive payment, security, and accelerator solution, resourceful multi-platform games, live, video, voice-social system, news stream, and together with gameloop communities on different social media, GameLoop aims to give one-stop game service to players, game publishers and publishers. Meanwhile, with 130M+ MAU worldwide, Gameloop PC & Mobile Distribution Channels provide one-stop distribution solutions and promotional resources for developers and publishers to reach high-value users in emerging markets to scale their games globally. Gameloop product matrix consists of Gameloop PC, Gameloop App, and Gameloop Store, giving players a better gaming experience and easier access to playing the latest and high-quality mobile games on PC and offering multiple localized payment channels. To interact with your friends and other gamers, GameLoop allows you to send text and voice messages.Gameloop™ is the world's leading brand of gaming platforms, providing comprehensive services for gamers, game developers and publishers. Like the online experience of gaming on a console, GameLoop allows you to enter a general lobby where you are soon placed into a group with other gamers from around the world. With Tencent’s games already being overwhelmingly multiplayer, the developers took the steps to enhance that experience by adding a built-in friend’s list to the interface. Keeping up with the trend of making gaming a social experience, GameLoop has found a way to incorporate opportunities for multiplayer at every turn. However, you may need to reinstall them to allow for the system to adjust to your PC’s frame rate capabilities. Be sure to take a thorough look through the emulator as it does come with its games already pre-installed. Some of those games include PUBG, Call of Duty, Candy Crush Saga, Clash Royale, Clash of Clans, Brawl Stars, and many more. Under the “GameCenter” window is where you’ll find the various games that GameLoop has in store for you. When it comes to your desired frame rate, that’s also up to you You can even use an Xbox One or PS4 controller for some of the games if you’d like. Best of all, GameLoop’s network is constantly adapting to your operating system to make sure that you aren’t experiencing any lag while you’re gaming. When it comes to your comfort level with the placement of the controls, that’s up to you. ![]() As the gamer, you are also given ultimate control over your experience. In addition to being the official emulation application for PlayerUnknown’s Battlegrounds (PUBG), the emulator has taken measures to ensure compatibility with most of the popular Android titles. GameLoop strives to offer a wide variety of features to enhance the gaming experience for users. While the emulator does work mainly with Tencent’s games, GameLoop has made sure to include some favorites from other developers as well. The interface caters directly to gamers with their strong attention to keyboard and mouse controls. GameLoop can turn your computer into a host for games exclusively found on smartphones and other mobile devices. In addition to allowing your operating system to emulate video game consoles. The beauty of Gameloop is that it takes it a step further. For example, if you had an emulator installed on your PC, you could play Call of Duty as if you were plugged into an Xbox One. What is an emulator?Įmulators are a way in which your operating system can behave as if it were a video game console. One of the most popular emulators out is GameLoop, an updated version of Tencent’s GameBuddy. This provides long-time gamers and novice gamers alike with a wide range of games to delve into. One of the ways in which they are doing so is through emulators. In a time where gaming is experiencing such a rise in popularity, we are seeing a surge in the different ways developers are capitalizing on it. ![]() The video won two MTV Video Music Awards in 2009 for Best Art Direction and Best Special Effects. It shows her survival, comeback, revenge on her boyfriend, and experiences on the way to fame. The accompanying music video was directed by Jonas Åkerlund and portrays Gaga as a doomed starlet, hounded by photographers, who is almost killed by her boyfriend (played by Alexander Skarsgård). ![]() It was also commercially successful, reaching top-ten positions in the music charts of Australia, Canada, Ireland, the United Kingdom, and the United States and topping the charts in the Czech Republic, Germany and Scotland. "Paparazzi" was critically acclaimed for its "fun-filled" and club-friendly nature. " LoveGame" initially had been planned as the third single release in the UK, but when its lyrics and music video were deemed potentially controversial, it was decided that "Paparazzi" would be released instead. The music video was released on May 29, 2009, and on J"Paparazzi" was released digitally in Ireland and the United Kingdom, and physically in Australia on July 10. Musically, it is an uptempo techno-pop and dance-pop ballad whose lyrics describe a stalker following somebody to grab attention and fame. The song portrays Gaga's struggles in her quest for fame, as well as balancing success and love. Gaga wrote and produced the song with Rob Fusari. It was released as the album's fifth and final single by Interscope Records. " Paparazzi" is a song by American singer Lady Gaga from her debut studio album, The Fame (2008). I would define an activity system as a growing group of communicative people with both a past and a future with similar goals both individually and as. I thought it was a group that did activities.like either a. Before we read this reading I had no prior knowledge to what an activity system was. activitysystemreading.pdf: File Size: 3488 kb: File Type: pdf: Download File. 277) from publication: A new approach to analysing human-related accidents by combined use of. It appears that activity systems have a deeper definition although they have 6 conditions just as discourse community does. Activity Theory: An Introduction for the Writing Classroom By: D. Download scientific diagram Elements of activity system model (adapted from Kain and Wardle 2014, p. From there, I may explain how knowledge of how this community functions can help to improve it. An activity system is very similar to a discourse community in my eyes. In my own research, I think I will first explain how my chosen discourse community meets each of these requirements. These communities must have a specific purpose. The group must communicate with themselves or they aren’t a discourse community at all because they do not share a discourse. ![]() For example, intercommunication and human interaction essentially suggest a researcher looks for the same thing. Kain and Wardle wrote, again borrowing their terms, that a discourse community is ongoing, object-directed, historically conditioned, dialectically structured, tool-mediated, and requires human interaction. Originator: Vygotsky, Leont’ev, Luria, and others starting in the 1920s. This essay has been submitted by a student. Categories: Society University/College: Sewanee University of the South. ![]() There exists a hierarchical analysis of motivated human action (levels of activity analysis). Essay Example on the Activity Theory and Activity Systems. People are socio-culturally embedded actors (not processors or system components). Swales wrote, to borrow some terms, that a discourse community has goals, has intercommunication between members, provides information and feedback, possesses its own genre, has a specific lexicon, and has certain expectations members must meet. Summary: Activity Theory is a framework or descriptive tool for a system. Analysis Of Activity Theory By Donna Kain And Elizabeth Wardle. Both provide six points to analyze when examining a community and in some places, those points overlap. In the essay Activity Theory: An Introduction for the Writing Classroom, Donna Kain and Elizabeth Wardle discuss a system, which allows for an easier way to analyze groups. Both John Swales “The Concept of Discourse Community” and Donna Kain and Elizabeth Wardle’s “Activity Theory: An Introduction for the Writing Classroom” share many similarities. Response to Kain and Wardle In order to fully understand a particular organization or population as a whole, it is crucial to explore and observe the various groups that are held. ![]() If you are using a cell phone, we suggest that you save a pdf file with a copy of the California drivers manual to your cell phone and keep it for future reference. Besides, who said you have to read the entire DMV book in one day? In fact, we recommend that you start preparing for your drivers permit test at least two weeks in advance! If you do this, you won't have to read more than 5 pages a day - anyone can do that!įor those of you who have found drivers handbook questions and answers useful - we've got some great news! We have prepared a California DMV practice test you can take online right now! In fact, we've got an entire batch of practice permit tests with multiple choice questions tailored to the 2023 DMV written test and they are all free! Head over to the practice test section and play with them as soon as you're done with the driver's handbook, we dare you to complete each and every one of them! Plenty of the space in the 2023 California drivers manual is taken up by illustrations of various on-road situations, images that take up entire pages, there's even a California drivers handbook practice test at the end of almost every chapter, so it's not like you will be reading 70 pages of fine print. It may seem like a touch too much, but it really isn't. California DMV permit test questions cover pretty much everything between pages 17 and 87. However, once you hit page 17 - it's time to buckle down and start paying attention. You can probably skip the first chapter that covers license requirements, the testing process, miscalleneous license information and the special section for minors if it does not apply to you, but be sure to check out cell phone restrictions for minors even if you are an adult - the DMV expects you to know them regardless of your age. Unlike driver manual in other states, the 2023 CA DMV drivers handbook is very condensed and straight to the point, you really cannot throw that much stuff out of it and will have to go over almost all of the 116 pages of the booklet. ![]() ![]() Don't make the same mistake, read the DMV drivers handbook and nail the permit test the first time you take it! The number of people who opt into taking the permit test without opening the drivers manual even once is simply mind-boggling. If we were to pick the most underappreciated, ignored and disregarded study resource for the DMV written test - the 2023 California drivers handbook would be our our choice and we would never give it a second thought. ![]() It is also because the same care was put into these parts of the pipeline as into the alignment stage. In part this is because SNAP avoids repeatedly reading and writing data files between stages that are implemented as different executable binaries. This code is typically about an order of magnitude faster than the typical samtools/Picard pipeline. In addition, SNAP includes code for sorting, duplicate marking and writing to BAM format. SNAP was written by skilled, professional computer systems programmers who have a deep understanding of the intricacies of computer architecture, which helps the code perform well independently of good algorithm design. Please refer to the SNAP paper (opens in new tab) for details. SNAP leverages a combination of three insights: increasing read lengths, which allow for fast hash-based location of reads using larger “seed” sequences increasing server memories, which allow trading memory to save CPU time (SNAP is designed for server machines with tens of gigabytes of RAM) and a novel algorithm for set intersection, edit distance algorithm, and pruning methodology that allow SNAP to reject most candidate locations without fully scoring them, dramatically reducing the cost of local alignment checks. The first step of this process is aligning each read to a known reference genome, so that later stages of the pipeline can view all the DNA for a specific location in the reference at once. Putting together these reads into a coherent whole is a significant computational challenge, with current pipelines taking many hundreds of CPU-hours per genome. However, current high-throughput sequencing technologies produce large numbers of short (~100-250 base) reads from random locations in the genome. For example, more and more cancer patients are having their germline and tumor genomes sequenced. With the cost of a WGS human genome below $1000, this technology is entering the realm of routine clinical practice. SNAP Quick Start Guide (opens in new tab)įAQ What is sequence alignment, and why is it important?Īs cheap DNA sequencing combined with more and more uses for sequence data increases the amount of sequence data available, there is a growing need for tools that can efficiently analyze large bodies of sequence data.ASHG 2014 SNAP Presentation, Ravi Pandya, (opens in new tab).Bolosky, Arun Subramaniyan, Matei Zaharia, Ravi Pandya, Taylor Sittler, and David Patterson. Fuzzy set intersection based paired-end short-read alignment (opens in new tab).Bolosky, Kristal Curtis, Armando Fox, David Patterson, Scott Shenker, Ion Stoica, Richard M. Faster and More Accurate Sequence Alignment with SNAP (opens in new tab).SNAPCommand for Windows (opens in new tab).SNAPCommand for Linux (opens in new tab).SNAP has one additional utility, the SNAPCommand program which sends alignment jobs to SNAP when it is running in daemon mode. SNAP v2.0.0 for OSX (64-bit) (opens in new tab).SNAP v2.0.1 for Linux (64-bit) (opens in new tab).SNAP v2.0.1 for Windows (64-bit) (opens in new tab).In addition, you can download binaries for Windows, Linux and OSX: SNAP is available under an Apache 2 license at /amplab/snap (opens in new tab). SNAP was developed by a team from Microsoft Research, the UC Berkeley AMP Lab (opens in new tab), and UCSF. SNAP does all of these tasks in a single tool, and is usually more than 10x faster than the standard samtools/Picard pipeline. Other aligners produce unsorted SAM (or in the case of Novoalign unsorted BAM) output, and require the use of other tools to compress, sort, mark duplicates and index the final output file. In addition to taking FASTQ (unprocessed reads) as input, it also accepts SAM and BAM (aligned reads). SNAP is also more full-featured than other aligners. When used with Haplotype Caller from the Genome Analysis Toolkit, SNAP produces better concordance with known-truth sets than other aligners for most of the genome-in-a-bottle and Illumina Platinum genomes. SNAP is from 2-5x faster than commonly used aligners like BWA-mem2 and Bowtie2, and 20x-nearly 30x faster than Novoalign. This is a computationally challenging problem because reference genomes are big (the human genome is over 3 billion base pairs long) and are often highly repetitive. It takes data from gene sequencing hardware that consists of short chunks of DNA (typically 70-300 base pairs long) called reads and determines where, how well and how unambiguously they match to a given reference genome. SNAP is a program that is part of a gene sequencing pipeline. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |